diff --git a/infer/man/man1/infer-capture.txt b/infer/man/man1/infer-capture.txt
index 161a69f8d..92ce190d0 100644
--- a/infer/man/man1/infer-capture.txt
+++ b/infer/man/man1/infer-capture.txt
@@ -267,8 +267,9 @@ CLANG OPTIONS
            Activates: Skip clang commands that Infer doesn't use to capture
            data (Conversely: --no-skip-non-capture-clang-commands)
 
-       --skip-translation-headers +path_prefix
-           Ignore headers whose path matches the given prefix
+       --skip-translation-headers +path_regex
+           Ignore declarations in headers whose path matches the given OCaml
+           regex from the start of the string during capture.
 
        --Xclang +string
            Pass values as command-line arguments to invocations of clang
diff --git a/infer/man/man1/infer-full.txt b/infer/man/man1/infer-full.txt
index aae52535e..11935bd6c 100644
--- a/infer/man/man1/infer-full.txt
+++ b/infer/man/man1/infer-full.txt
@@ -1203,8 +1203,9 @@ OPTIONS
            data (Conversely: --no-skip-non-capture-clang-commands)       
     See also infer-capture(1).
 
-       --skip-translation-headers +path_prefix
-           Ignore headers whose path matches the given prefix           See also infer-capture(1).
+       --skip-translation-headers +path_regex
+           Ignore declarations in headers whose path matches the given OCaml
+           regex from the start of the string during capture.           See also infer-capture(1).
 
        --source-files
            Activates: Print source files discovered by infer (Conversely:
diff --git a/infer/man/man1/infer.txt b/infer/man/man1/infer.txt
index 1fd5e343c..bca6fa8f3 100644
--- a/infer/man/man1/infer.txt
+++ b/infer/man/man1/infer.txt
@@ -1203,8 +1203,9 @@ OPTIONS
            data (Conversely: --no-skip-non-capture-clang-commands)       
     See also infer-capture(1).
 
-       --skip-translation-headers +path_prefix
-           Ignore headers whose path matches the given prefix           See also infer-capture(1).
+       --skip-translation-headers +path_regex
+           Ignore declarations in headers whose path matches the given OCaml
+           regex from the start of the string during capture.           See also infer-capture(1).
 
        --source-files
            Activates: Print source files discovered by infer (Conversely:
diff --git a/infer/src/base/Config.ml b/infer/src/base/Config.ml
index 4866e89c2..edb59e0d1 100644
--- a/infer/src/base/Config.ml
+++ b/infer/src/base/Config.ml
@@ -2330,7 +2330,9 @@ and skip_non_capture_clang_commands =
 and skip_translation_headers =
   CLOpt.mk_string_list ~deprecated:["skip_translation_headers"] ~long:"skip-translation-headers"
     ~in_help:InferCommand.[(Capture, manual_clang)]
-    ~meta:"path_prefix" "Ignore headers whose path matches the given prefix"
+    ~meta:"path_regex"
+    "Ignore declarations in headers whose path matches the given OCaml regex from the start of the \
+     string during capture."
 
 
 and source_preview =
diff --git a/infer/src/clang/cLocation.ml b/infer/src/clang/cLocation.ml
index a7815852c..2bceaf526 100644
--- a/infer/src/clang/cLocation.ml
+++ b/infer/src/clang/cLocation.ml
@@ -20,14 +20,19 @@ let clang_to_sil_location default_source_file clang_loc =
   Location.{line; col; file}
 
 
+let matches_skip_translation_headers =
+  match Config.skip_translation_headers with
+  | [] ->
+      fun _ -> false
+  | reg_list ->
+      let regex = Re.Str.regexp (String.concat ~sep:"\\|" reg_list) in
+      fun file -> Re.Str.string_match regex file 0
+
+
 let source_file_in_project source_file =
   let file_in_project = SourceFile.is_under_project_root source_file in
-  let rel_source_file = SourceFile.to_string source_file in
-  let file_should_be_skipped =
-    List.exists
-      ~f:(fun path -> String.is_prefix ~prefix:path rel_source_file)
-      Config.skip_translation_headers
-  in
+  let source_file_path = SourceFile.to_string source_file in
+  let file_should_be_skipped = matches_skip_translation_headers source_file_path in
   file_in_project && not file_should_be_skipped